If your mitral valve can't be repaired, your doctor may recommend mitral valve replacement. In this procedure, your doctor removes the mitral valve and replaces it with a mechanical valve or a biological tissue valve. Biological tissue valves often eventually need to be replaced, as they degenerate over time. If you have a mechanical valve, you'll need to take blood-thinning medications for the rest of your life to prevent blood clots. Doctors will discuss with you the risks and benefits of each type of valve and discuss which valve may be appropriate for you.